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Shizuka Mita Selected Research

dienogest

3/2021Identification of biomarkers for drug-resistant endometriosis using clinical proteomics.
7/2017Dienogest inhibits C-C motif chemokine ligand 20 expression in human endometriotic epithelial cells.
3/2015Dienogest, a synthetic progestin, down-regulates expression of CYP19A1 and inflammatory and neuroangiogenesis factors through progesterone receptor isoforms A and B in endometriotic cells.
2/2014Dienogest inhibits nerve growth factor expression induced by tumor necrosis factor-α or interleukin-1β.
12/2011Dienogest inhibits Toll-like receptor 4 expression induced by costimulation of lipopolysaccharide and high-mobility group box 1 in endometrial epithelial cells.
1/2011Dienogest, a synthetic progestin, inhibits prostaglandin E2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system.
10/2009Dienogest, a synthetic progestin, inhibits the proliferation of immortalized human endometrial epithelial cells with suppression of cyclin D1 gene expression.

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Shizuka Mita Research Topics

Disease

8Endometriosis
03/2021 - 10/2009
3Inflammation (Inflammations)
03/2021 - 01/2011
2Cysts
03/2021 - 11/2017
2Pain (Aches)
03/2015 - 02/2014
2Infections
08/2008 - 11/2004
1Carcinoma (Carcinomatosis)
03/2021
1Carcinogenesis
03/2021
1Uterine Diseases (Endometrial Disease)
01/2011

Drug/Important Bio-Agent (IBA)

7dienogestFDA Link
03/2021 - 10/2009
3Progesterone Receptors (Progesterone Receptor)IBA
07/2017 - 10/2009
3Aromatase (CYP19)IBA
03/2015 - 01/2011
3Therapeutic UsesIBA
02/2012 - 01/2011
2Prostaglandins EIBA
02/2012 - 01/2011
2Peptidoglycan (Murein)IBA
08/2008 - 11/2004
1LactoferrinIBA
03/2021
1Peroxidase (Myeloperoxidase)IBA
03/2021
1Pharmaceutical PreparationsIBA
03/2021
1Insulin (Novolin)FDA Link
03/2021
1Peptide Hydrolases (Proteases)FDA Link
03/2021
1Progestins (Progestagens)IBA
03/2021
1Proteins (Proteins, Gene)FDA Link
03/2021
1Lipocalin-2IBA
03/2021
1Biomarkers (Surrogate Marker)IBA
03/2021
1human AZU1 proteinIBA
03/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2017
1ChemokinesIBA
07/2017
1LigandsIBA
07/2017
1Protein Isoforms (Isoforms)IBA
03/2015
1Nerve Growth Factor (NGF)IBA
02/2014
1ProstaglandinsIBA
01/2011
1Pattern Recognition ReceptorsIBA
08/2008
1Diaminopimelic AcidIBA
08/2008

Therapy/Procedure

1Oral Administration
03/2015